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260.611.01
Principles of Immunology I

Location
East Baltimore
Term
1st Term
Department
Molecular Microbiology and Immunology
Credit(s)
4
Academic Year
2013 - 2014
Instruction Method
TBD
Class Time(s)
Tu, Th, 8:30 - 10:20am
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Frequency Schedule
Every Year
Prerequisite

A course in advanced biology

Description
Introduces biological concepts of immunology; molecular nature of antigens; molecular basis for antibody and T-cell receptor structure and diversity; complement; hypersensitivity reactions; cellular basis for the immune response; cell-mediated immunity; adhesion molecules and coreceptors cell activation; cytokines and other soluble mediators; major histocompatibility complex (MHC) antigens; tumor immunology; transplantation immunobiology; mechanisms of resistance to microorganisms; tolerance; autoimmunity; and immuno-deficiency.
Learning Objectives
Upon successfully completing this course, students will be able to:
  1. Define the tissue, cellular and molecular components that constitute the vertebrate innate and adaptive immune system
  2. Explain the generation of lymphocyte antigen receptors and the molecular and cellular basis for diversity and specificity of receptors on immune cells
  3. Define the basis for antigen presentation to T cells
  4. Define the basis for recognition of self and non-self recognition
  5. Define the development and survival of lymphocytes
  6. Explain the major signaling pathways used by immune cells
  7. Define T cell-mediated and B cell-mediated immunity
Special Comments

Required for MMI students.