260.655.01
Protein BioInformatics and Structure
Location
East Baltimore
Term
4th Term
Department
Molecular Microbiology and Immunology
Credit(s)
3
Academic Year
2012 - 2013
Instruction Method
TBD
Tu, Th, 3:30 - 4:50pm
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Course Instructor(s)
Juergen Bosch
Contact Name
Sean Prigge
Contact Email
Frequency Schedule
Every Other Year
Resources
Prerequisite
Introduction to Molecular Biology (120.602) or consent of instructor
Provides students with an overview of protein bioinformatics including computational and experimental approaches. Introduces amino acid and protein physical properties as well as the alignment and evolution of protein sequences. Presents protein structure and methods of structure determination as well as the use of protein databases and software for visualizing proteins and generating publication quality figures. Discusses methods for secondary and tertiary protein structure prediction including homology modeling. Also covers methods for modeling small/molecule-protein interactions within the context of rational drug discovery and design. Finally, introduces students to experimental and computational aspects of mapping protein interaction networks.
Jointly Offered With
Three Friday computer labs will provide students with practical experience with web-based tools.