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# 140.622.01 STATISTICAL METHODS IN PUBLIC HEALTH II

Department:
Biostatistics
Term:
2nd term
Credits:
4 credits
Academic Year:
2012 - 2013
Location:
East Baltimore
Class Times:
• Tu Th,  10:30 - 11:50am
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Contact:
Marie Diener-West
Course Instructors:
Description:

Presents use of likelihood functions, confidence intervals, and hypothesis tests to draw scientific inferences from public health data. Discusses null and alternative hypotheses, Type I and II errors, and power. Develops parametric and non-parametric statistical methods for comparing multiple groups (ANOVA). Also introduces measures of association and simple linear regression. Addresses methods for planning a study, including stratification, balance, sampling strategies, and sample size.

Learning Objectives:

Upon successfully completing this course, students will be able to:

1. Use statistical reasoning to formulate public health questions in quantitative terms [1.1 Distinguish the summary measures of association applicable to retrospective and prospective study designs; 1.2 Distinguish between the appropriate regression models
2. Design and interpret graphical and tabular displays of statistical information [2.1 Use the statistical analysis package Stata to construct statistical tables and graphs of journal quality];
3. Distinguish among the underlying probability distributions for modeling continuous, categorical, binary and time-to-event data; 3.2 Calculate the sample size necessary for estimating either a continuous or binary outcome in a single group; 3.3 Estimate the sample size necessary for determining a statistically significant difference in either a continuous or binary outcome between two groups; 3.4 Recognize the assumptions required in performing statistical tests assessing relationships between an outcome and a risk factor
4. Use statistical methods for inference, including confidence intervals and tests, to draw valid public health inferences from study data 4.1 Estimate two proportions and their difference, and confidence intervals for each. Interpret the interval estimates within a scientific context. Recognize the importance of other sources of uncertainty beyond those captured by the confidence interval; 4.2 Estimate an odds ratio or relative and its associated confidence interval. Explain the difference between the two and when each is appropriate; 4.3 Perform and interpret one-way analysis of variance to test for differences in means among three or more populations. Evaluate whether underlying probability model assumptions are appropriate; 4.4 Contrast mean outcomes among pairwise groups using multiple comparisons procedures; 4.5 Interpret the correlation coefficient as a measure of the strength of a linear association between a continuous response variable and a continuous predictor variable
Methods of Assessment:
Student evaluation based on problem sets and exams.
Enrollment Restriction:
For MPH, DrPH, "special students" and MHS degree candidates in departments to be determined
Instructor Consent:
Consent required for some students
Consent Note:

Consent required for non-PH students

For consent, contact:
mdiener@jhsph.edu
Prerequisite:

140.621

Special Comments:
One 90-minute lab per week, lab is 140.922. As soon as you register for the course, please also register for one section of 140.922. Course Materials Fee is \$40.00.