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120.627.01 STEM CELLS AND THE BIOLOGY OF AGING AND DISEASE

Term: 2nd term
Credits: (3 credits)
Academic Year: 2012 - 2013
Description:

Focuses on stem cell properties and on the biology of stem cells in the context of normal development, aging, tissue homeostasis, and disease settings including cancer. Also discusses the potential application of stem cells to the treatment of human disease, and emphasizes current literature.
Student Evaluation: Evaluation of performance in this class is based on class participation, knowledge of reading assignments, presentations to the class and/or short paper. Class participation is an integral part of the grade.
Learning Objective:

After completing this course, the student should be able to: (1) describe the unique properties of stem cells; (2) explain the similarities and differences in the functioning of stem cells in the male and female reproductive tracts, including the influence of the niche on their functioning; (3) explain how stem cells differ when situated in a low- versus high-turnover tissue setting; (4) describe the changes in stem cells that may lead to cancer, and the causes of these changes; and (5) appraise the possibility of using stem cells therapeutically for the treatment of human disease.
Location: Baltimore
Class Times:
  • Tuesday 3:30 - 4:50
  • Thursday 3:30 - 4:50
Enrollment Minimum: 10
Instructor Consent: No consent required
For consent, contact: dbarbosa@jhsph.edu
Prerequisite:

a course in biochemistry or molecular biology or cell biology (undergrad or graduate)
Auditors Allowed: Yes, with instructor consent
Grading Restriction: Letter Grade or Pass/Fail
Catalog Subcommittee Actions: CourseOfferRationaleNote, ContactPerson, ContactEmail, CPInstructor, .07/19/2012; TermId, FrequencySchedule, CourseLocation, CourseFormat, CourseFormat, IRBSurvey, AuditorsAllowedId, ExpectedEnrollNumber, CourseOfferRationaleNote, ContactPerson, ContactEmail, RepeatableRetakable, ScheduleTypeId, LabScheduleTypeId, .08/08/2011;