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120.627.01 STEM CELLS AND THE BIOLOGY OF AGING AND DISEASE

Term: 2nd term
Credits: 3 credits
Contact: Barry Zirkin
Academic Year: 2011 - 2012
Course Instructors:
Description:

Focuses on stem cell properties and on the biology of stem cells in the context of normal development, aging, tissue homeostasis, and disease settings including cancer. Also discusses the potential application of stem cells to the treatment of human disease, and emphasizes current literature.

Learning Objective(s):
Upon successfully completing this course, students will be able to:
describe the unique properties of stem cells
Explain the similarities and differences in the functioning of stem cells in the male and female reproductive tracts, including the influence of the niche on their functioning
Explain how stem cells differ when situated in a low- versus high-turnover tissue setting
Describe the changes in stem cells that may lead to cancer, and the causes of these changes
Appraise the possibility of using stem cells therapeutically for the treatment of human disease

Methods of Assessment: Evaluation of performance in this class is based on class participation, knowledge of reading assignments, presentations to the class and/or short paper. Class participation is an integral part of the grade.
Location: East Baltimore
Class Times:
  • Tuesday 3:30 - 4:50
  • Thursday 3:30 - 4:50
Enrollment Minimum: 10
Instructor Consent: No consent required
Prerequisite:

a course in biochemistry or molecular biology or cell biology (undergrad or graduate)

Auditors Allowed: Yes, with instructor consent
Grading Restriction: Letter Grade or Pass/Fail