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Course Catalog

120.608.01 GENOMICS FOR PUBLIC HEALTH

Term: 4th term
Credits: (3 credits)
Contact: Roger McMacken
Academic Year: 2012 - 2013
Description:

Introduces genomics and modern genetic technologies, emphasizing their application to significant public health problems, to students who have limited prior coursework in molecular biology or molecular genetics. Integrates lectures and discussions with computer exercises in laboratory sessions. Topics include fundamental principles of molecular biology; genome sequencing and structure; gene cloning; mapping of human disease genes; use of DNA microarrays, protein microarrays, and next generation rapid DNA sequencing methodologies in analysis and treatment of human disease; comparative genomics of model and pathogenic organisms; epigenomics and metagenomics; and genetically modified organisms.
Student Evaluation: Student evaluation based on four online quizzes (1/4 of total), two computer lab exercises (1/4 of total) and a final exam (1/2 of total).
Learning Objective:

This course should make it possible for you to do the following: describe the organization of the human genome and the genomes of selected model organisms; explain how human disease genes are mapped; analyze DNA, RNA, or protein sequences through the use of public domain databases and algorithms; explain how DNA microarrays and protein microarrays can be used to analyze human disease in individuals and populations; describe basic recombinant DNA, proteomic, and biotechnological methodologies used in the analysis of human disease.
Location: Baltimore
Class Times:
  • Tuesday 1:30 - 2:50
  • Thursday 1:30 - 2:50
Lab Times:
  • Tu Th 1:30 - 2:50 (1)
Enrollment Minimum: 10
Instructor Consent: No consent required
For consent, contact: rmcmacken@jhsph.edu
Prerequisite:

A college level course in biology.
Auditors Allowed: Yes, with instructor consent
Grading Restriction: Letter Grade or Pass/Fail
Catalog Subcommittee Actions: CourseLearningObj, Prerequisite, StudentEval, TargetAud, CourseLocation, CourseFormat, IRBSurvey, AuditorsAllowedId, CourseOfferRationaleNote, ContactPerson2, ContactEmail2, ScheduleTypeId, CourseLearningObjectives, LabScheduleTypeId, CPInstructor, .12/19/2011;