Research Studies and Other Projects

The research environment of the Center is multi-institutional, involving faculty and collaboration across multiple departments in the Johns Hopkins Bloomberg School of Public Health, the School of Medicine, and other institutions. Research activities include the design, conduct, and analysis of clinical trials; performance of systematic reviews and meta-analysis of the research evidence; methodological work, such as studies of bias in study design and dissemination of results; and examination of the language and nomenclature of trials.

The subject matter of the clinical trials and systematic reviews conducted by the Center covers a variety of health conditions including but not limited to the ocular complications of AIDS, uveitis, non-arteritic anterior ischemic optic neuropathy, Alzheimer's disease, childhood asthma, emphysema, Barrett's esophagus, non-alcoholic steatohepatitis, and dysfunctional uterine bleeding.

Listed below are current or recent research studies:

Clinical Trials/Followup

Ongoing

American Lung Association - Asthma Clinical Research Centers (ALA-ACRC)
Citalopram for Agitation in Alzheimer's Disease (CitAD)
Multicenter Uveitis Steroid Treatment Trial (MUST)
The Studies of Ocular Complications of AIDS (SOCA)
Apathy in Dementia Methylphenidate Trial (ADMET)
The Tinnitus Retraining Therapy Trial (TRTT)
Biomarkers of Cognitive Decline Among Normal Individuals: the BIOCARD Cohort Study Extension (BIOCARD-SE)
International Collaborative Effort on Chronic Obstructive Lung Disease: Exacerbation Risk Index Cohorts (ICE COLD ERIC)

Completed Followup/Undergoing Analysis

Alzheimer's Disease Anti-Inflammatory Prevention Trial, Follow-up Study (ADAPT-FS)
Depression in Alzheimer's Disease Study - Phase 2 (DIADS-2)
The Ischemic Optic Neuropathy Decompression Trial (IONDT)
Surgical Treatments Outcomes Project for Dysfunctional Uterine Bleeding (STOP-DUB)
Sleep Heart Health Study (SHHS)

Archived

Chemoprevention Barrett's Esophagus Trial (CBET)
Preservation of Vascular Access Study (PVAS)
Wegener's Granulomatosis Etanercept Trial (WGET)
TrialsCentral™ - Your source for online clinical trials information (TrialsCentral)

Systematic Reviews

Cochrane Collaboration Eyes and Vision Group (CEVG)
United States Cochrane Center (USCC)

Methods Reserch

Project ImpACT: Important Achievements of Clinical Trials (ImpACT)
PROactive: Development of a Patient-Reported Outcome for Physical Activity in COPD

Data Collection Completed

A+ Asthma Early Intervention for Asthma Management (A+ Asthma)