In April 2008, Rajendra Shukla was appointed a Joint Secretary in the Ministry of Health, Government of India, New Delhi with responsibilities for policy formulation and program implementation in respect of control of vector borne diseases and tuberculosis in India. He is also heading a team of ministry officials and consultants charged with the responsibility of developing new super speciality, tertiary care, teaching and research institutions in the public sector in India. He is the nodal officer in the ministry for policy and legal matters and international collaboration & cooperation in regard to his portfolios.