Biology of Healthy Aging Program
Overview
Key Findings/Program Goals
Key Personnel
Contact

Ongoing Projects

Inflammatory Phenotype Development in Population Studies

Genetics Studies Related to Inflammation and Apoptosis

Immune System Senescence Studies

Frail and Anemic Mouse Models

Translation to Humans:

• Assess impact of inflammation and anesthesia on post-op delirium and cognition
• Recruiting 200 elective surgery patients
  • Measure IL-6, cortisol, cognition, pre-op
  • Measure delirium in perioperative period
  • Measure cognition at 4 months

Genetics:

• Establish at-risk genotypes for frailty and late life decline
• Use results as clues to identify biological pathways implicated in aging and metabolic processes