Faculty - Center on Aging and Health

Esther Oh
Assistant Professor

Academic Degrees
M.D.

Departmental Affiliation
Department of Medicine
Division of Geriatrics and Gerontology

Joint Departmental Affiliations
Division of Neuropathology

Departmental Address
5505 Hopkins Bayview Circle, Baltimore, MD 21224

Email: eoh9@jhmi.edu

Collexis expertise and publication web link

For more information visit my personal web page.

Research and Professional Experience

Dr. Oh’s research interest is in developing biological marker for pre-clinical stage of Alzheimer’s disease (AD). Her current research involves using transgenic models of AD to develop peripheral injection of monoclonal antibody against amyloid-beta as a tool to detect a level of amyloid-beta that would be correlative to amyloid-beta level in the brain. Her clinical practice is in the Memory clinic at the Johns Hopkins University.

Keywords

Alzheimer’s disease, dementia, biomarker, transgenic mouse model of Alzheimer’s disease

Honors and Awards

John A. Hartford Foundation Fellowship in Geriatric Medicine, 1990

de Kiewiet Summer Research Scholarship, 1990

Okayama University International Exchange Scholarship, 1992

National Institute of Health (NIH) Summer Research Fellowship, 1995

National Institute on Aging (NIA) Research Training in Gerontology and Geriatric Medicine 2002-2004

Technical Assistance Workshop, National Institute on Aging (NIA) 2003

Summer Institute on Aging Research (NIA) 2005

Selected Publications

1. Tabuchi A, Sano K, Oh E, Tsuchiya T, Tsuda M. Modulation of AP-I activity by nitric oxide (NO) in vitro: NO-mediated modulation of AP-I. FEBS Letters, 1994; 351:123-127.

2. Ohtani K, Sakurai H, Oh E, Iwata E, Tsuchiya T, Tsuda M. Involvement of protein kinase C in calcium signaling pathway to activation of AP-I DNA-binding activity evoked via NMDA and voltage-gated calcium channels. Journal of Neurochemistry, 1995;65(2):605-614.

3. Tabuchi A, Oh E, Taoka A, Sakurai H, Tsuchiya T, Tsuda M. Rapid attenuation of AP-I transcriptional factors associated with nitric oxide (NO) – mediated neuronal cell death. The Journal of Biological Chemistry, 1996; 271:31061-31067.

4. Oh ES, Savonenko AV, King JF, Tucker SM, Rudow GL, Xu G, Borchelt DR, Troncoso JC. Amyloid Precursor Protein Increases Cortical Neuron Size in Transgenic Mice Neurobiology of Aging, Epub (2/08) in press

5. Oh ES, Troncoso JC, Fangmark Tucker SM. Maximizing the potential of plasma amyloid-beta as a diagnostic biomarker for Alzheimer’s disease, Neuromolecular Medicine, 2008;10 (3):195-207 PMC2558671