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Older Americans Independence Center
Publications, by year
2011 - 2010 - 2009 - 2008 - 2007 - 2006 - 2005 - 2004

2011 (published or in press)
Abadir PM, Foster DB, Crow M, Cooke CA, Rucker JJ, Jain A, Smith BJ, Burks TN, Cohn RD, Fedarko NS, Carey RM, O'Rourke B, Walston JD. Identification and characterization of a functional mitochondrial angiotensin system. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14849-54. Epub 2011 Aug 18. PMID:21852574.

Abadir PM. The frail renin-angiotensin system. Clin Geriatr Med. 2011 Feb;27(1):53-65. PMID:21093722.

Abadir PM, Walston JD, Carey RM, Siragy HM. Angiotensin II Type-2 Receptors Modulate Inflammation Through Signal Transducer and Activator of Transcription Proteins 3 Phosphorylation and TNF? Production. J Interferon Cytokine Res. 2011 Feb 2. [Epub ahead of print]. PMID: 21288138.

Agbedia OO, Varma VR, Seplaki CL, Seeman TE, Fried LP, Li L, Harris GC, Rebok GW, Xue QL, Tan EJ, Tanner E, Parisi JM, McGill S, Carlson MC. Blunted diurnal decline of cortisol among older adults with low socioeconomic status. Ann N Y Acad Sci. 2011 Aug;1231(1):56-64. doi: 10.1111/j.1749-6632.2011.06151.x. PMID:21884161.

Benke KS, Carlson MC, Doan BQ, Walston JD, Xue QL, Reiner AP, Fried LP, Arking DE, Chakravarti A, Fallin MD. The association of genetic variants in interleukin-1 genes with cognition: Findings from the cardiovascular health study. Exp Gerontol. 2011 Sep 24. [Epub ahead of print]. PMID:21968104.

Burks TN, Andres-Mateo, E. Marx R, Mejias R. Van Erp C, Simmers JL, Walston JD, Ward CW, Cohn RD. Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia. Sci Trans Med. 2011 May 11;3(82):82ra37. PMID:21562229.

Burks TN and Cohn RD. Role of TGF-b signaling in inherited and acquired myopathies. Skeletal Muscle. 2011 May 4;1(1):19. PMID:21798096.

Calvi CL, Podowski M, D'Alessio FR, Metzger SL, Misono K, Poonyagariyagorn H, Lopez-Mercado A, Ku T, Lauer T, Cheadle C, Talbot CC Jr, Jie C, McGrath-Morrow S, King LS, Walston J, Neptune ER. Critical transition in tissue homeostasis accompanies murine lung senescence. PLoS One. 2011;6(6):e20712. Epub 2011 Jun 21. PMID:21713037

Ho YY, Matteini AM, Beamer BA, Fried LP, Xue Q-L, Arking DE, Chakravarti A, Walston JD, Fallin D. Exploring Biologically Relevant Pathways in Frailty. J Gerontol A Biol Sci Med Sci. 2011 September;66A(9):975–979. PMID: 21743092.

Kalyani RR, Metter EJ, Ramachandran R, Chia CW, Saudek CD, Ferrucci L. Glucose and Insulin Measurements From the Oral Glucose Tolerance Test and Relationship to Muscle Mass. J Gerontol A Biol Sci Med Sci. 2011 Feb 24. [Epub ahead of print] PMID:21350243.

Ko F, Yu Q, Xue QL, Yao W, Brayton C, Yang H, Fedarko N, Walston J. Inflammation and mortality in a frail mouse model. Age (Dordr). 2011 Jun 2. [Epub ahead of print]. PMID:21633802.

Leng SX, Tian X, Matteini A, Li H, Hughes J, Jain A, Walston JD, Fedarko NS. IL-6-independent association of elevated serum neopterin levels with prevalent frailty in community-dwelling older adults. Age Ageing. 2011 Jul;40(4):475-81. Epub 2011 May 17. PMID: 21586579.

Leng SX, Qu T, Semba RD, Li H, Yao X, Nilles T, Yang X, Manwani B, Walston JD, Ferrucci L, Fried LP, Margolick JB, Bream JH. Relationship between cytomegalovirus (CMV) IgG serology, detectable CMV DNA in peripheral monocytes, and CMV pp65(495-503)-specific CD8 (+) T cells in older adults. Age (Dordr). 2011 Jan 28. [Epub ahead of print]. PMID: 21274637.

Leng SX, Li HF, Xue Q-L, Yao X, Tian J, Yang X, Ferrucci L, Fedarko N, Fried LP, Semba RD. Association of detectable cytomegalovirus (CMV) DNA in monocytes rather than positive CMV IgG serology with elevated neopterin levels in community-dwelling older adults. Exp Gerontol. 2011 Aug;46(8):679-84. Epub 2011 Apr 13. PMID: 21513787.

Lin FR, Thorpe R, Gordon-Salant S, Ferrucci L. Hearing Loss Prevalence and Risk Factors Among Older Adults in the United States. J Gerontol A Biol Sci Med Sci. 2011 Feb 27. [Epub ahead of print].

Moseley KF, Dobrosielski DA, Stewart Kj, Jan De Beur SM, Sellmeyer DE. Lean mass and fat mass predict bone mineral density in middle-aged individuals with non-insulin -requiring type 2 diabetes mellitus. Clin Endocrinol (Oxf). 2011 May;74(5):565-71. doi: 10.1111/j.1365-2265.2010.03965.x. Epub 2010 Dec 24.

Reinke C, Bevans-Fonti S, Grigoryev DN, Drager LF, Myers AC, Wise RA, Schwartz AR, Mitzner W, Polotsky VY. Chronic intermittent hypoxia induces lung growth in adult mice. Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L266-73. Epub 2010 Dec 3. PMID:21131398.

Roy CN. Anemia in frailty. Clin Geriatr Med. 2011 Feb;27(1):67-78. PMID:21093723.

Walston JD. Frailty. Preface. Clin Geriatr Med. 2011 Feb;27(1):xi. No abstract available. PMID:21093717.

Weiss CO. Frailty and chronic diseases in older adults. Clin Geriatr Med. 2011 Feb;27(1):39-52. Review. PMID:21093721.

Xue QL. The frailty syndrome: definition and natural history. Clin Geriatr Med. 2011 Feb;27(1):1-15. Review. PMID:21093718.

Xue Q-L, Walston JD, Fried LP, Beamer BA. Rate of decline in grip strength predicts the risk of falling, physical disability, and frailty: The Women’s Health and Aging Study. Arch Intern Med. 2011 Jun 27;171(12):1119-21. No abstract available. PMID:21709116.

Yao X, Hamilton R, Weng N-P, Xue Q-L, Bream JH, Tian J, Yeh S-H, Resnick B, Xu XY, Walston JD, Fried LP, Leng SX. Frailty is associated with poor vaccine-induced antibody response and increased influenza infection in community-dwelling older adults. Vaccine. 2011 Jul 12;29(31):5015-21. Epub 2011 May 10. PMID:21565245..

Yao X, Li H, Leng SX. Inflammation and immune system alterations in frailty. Clin Geriatr Med. 2011 Feb;27(1):79-87. PMID: 21093724.

Zhang T, Mullane PC, Periz G, Wang J. TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling. Hum Mol Genet. 2011 Mar 11. [Epub ahead of print] PMID: 21355045.

2010
Crentsil V. Mechanistic contribution of carnitine deficiency to geriatric frailty. Ageing Res Rev. 2010 Jul;9(3):265-8. Epub 2010 Mar 17. PMID: 20223299.

Crentsil V, Ricks MO, Xue QL, Fried LP. A pharmacoepidemiologic study of community-dwelling, disabled older women: Factors associated with medication use. Am J Geriatr Pharmacother. 2010 Jun;8(3):215-24. PMID: 20624611.

Franckowiak SC, Dobrosielski DA, Reilley SM, Walston JD, Andersen RE. Maximal Heart Rate Prediction in Adults that are Overweight or Obese. J Strength Cond Res. 2010 Nov 24. [Epub ahead of print]. PMID: 21116203.

Makary MA, Segev DL, Fried LP, Syin D, Bandeen-Roche K, Patel P, Devgan L, Holzmueller CG, Tian J, Pronovost PR. Frailty as a Predictor of Surgical Outcome in Older Patients. J Am Coll Surg. 2010 Jun;210(6):901-8. Epub 2010 Apr 28. PMID: 20510798.

Matteini AM, Walston JD, Bandeen-Roche K, Arking DE, Allen RH, Fried LP, Chakravarti A, Stabler SP, Fallin MD. Transcobalamin-II variants, decreased vitamin B12 availability and increased risk of frailty. J Nutr Health Aging. 2010 Jan;14(1):73-7. PMID: 20082058.

Matteini AM, Fallin MD, Kammerer CM, Schupf N, Yashin AI, Christensen K, Arbeev KG, Barr G, Mayeux R, Newman AB, Walston JD. Heritability Estimates of Endophenotypes of Long and Health Life: The Long Life Family Study. J Gerontol A Biol Sci Med Sci. 2010 Sep 2. [Epub ahead of print]. PMID: 20813793

Moore AZ, Biggs ML, Matteini AM, O’Connor A, McGuire S, Beamer B, Fallin MD, Fried LP, Walston J, Chakravarti A, Arking DE. Polymorphisms in the mitochondrial DNA control region and frailty in older adults. PLoS One. 2010 Jun 10;5(6):e11069. PMID: 20548781. PMCID: PMC2883558.

Rosenberg PB, Mielke MM, Xue QL, Carlson MC. Depressive symptoms predict incident cognitive impairment in cognitive healthy older women. Am J Geriatr Psychiatry. 2010 Mar;18(3):204-11. PMID: 20224517.

Roy CN. Anemia of inflammation. Hematology Am Soc Hematol Educ Program. 2010;2010:276-80. PMID:21239806.

Semba RD, Patel KV, Ferrucci L, Sun K, Roy CN, Guralnik JM, Fried LP. Serum antioxidants and inflammation predict red cell distribution width in older women: The Women's Health and Aging Study I. Clin Nutr. 2010 Oct;29(5):600-4. 2010 Mar 22. [Epub ahead of print] PMID: 20334961

Sourial N, Wolfson C, Bergman H, Zhu B, Karunananthan S, Quail J, Fletcher J, Weiss D, Bandeen-Roche K, Béland F. A correspondence analysis revealed frailty deficits aggregate and are multidimensional. J Clin Epidemiol. 2010 Jun;63(6):638-46. Epub 2009 Nov 6.

Sourial N, Wolfson C, Zhu B, Quail J, Fletcher J, Karunananthan S, Bandeen-Roche K, Béland F, Bergman H. Correspondence analysis is a useful tool to uncover the relationships among categorical variables. J Clin Epidemiol. 2010 Jun;63(6):647-54. Epub 2009 Oct 31.

Tanaka T, Roy CN, Yao W, Matteini A, Semba RD, Arking D, Walston JD, Fried LP, Singleton A, Guralnik J, Abecasis GR, Bandinelli S, Longo DL, and Ferrucci L. A Genome-Wide Association Analysis of Serum Iron Concentrations. Blood 2010; 115(1):94-96. PMID: 19880490

Varadhan R, Weiss CO, Segal JB, Wu AW, Scharfstein D, Boyd C. Evaluating health outcomes in the presence of competing risks: a review of statistical methods and clinical applications. Med Care. 2010 Jun;48(6 Suppl):S96-105. PMID: 20473207

Wang GC, Talor MV, Rose NR, Cappola AR, Chiou RB, Weiss C, Walston JD, Fried LP, Caturegli P. Thyroid autoantibodies are associated with a reduced prevalence of frailty in community-dwelling older women. J Clin Endocrinol Metab. 2010 Mar;95(3):1161-8. Epub 2010 Jan 8. PMID: 20061418.

Wang GC, Kao WH, Murakami P, Xue QL, Chiou RB, Detrick B, McDyer JF, Semba RD, Casolaro V, Walston JD, Fried LP. Cytomegalovirus Infection and the Risk of Mortality and Frailty in Older Women: A Prospective Observational Cohort Study. Am J Epidemiol. 2010 May 15;171(10):1144-52. Epub 2010 Apr 16. PMID: 20400465.

Weiss CO, Hoenig HH, Varadhan R, Simonsick EM, Fried LP. Relationships of cardiac, pulmonary, and muscle reserves and frailty to exercise capacity in older women. J Gerontol A Biol Sci Med Sci. 2010 Mar;65(3):287-94. Epub 2009 Oct 12. PMID: 19822621.

Xue QL, Beamer BA, Chaves PH, Guralnik JM, Fried LP. Heterogeneity in rate of decline in grip, hip, and knee strength and the risk of all-cause mortality: the Women's Health and Aging Study II.J Am Geriatr Soc. 2010 Nov;58(11):2076-84. PMID:21054287

2009
Alipanah N, Varadhan R, Sun K, Ferrucci L, Fried LP, Semba RD. Low serum carotenoids are associated with a decline in walking speed in older women. J Nutr Health Aging. 2009 Mar;13(3):170-5. PMID: 19262947.

Bandeen-Roche K, Walston JD, Huang Y, Semba RD, Ferrucci L. Measuring systemic inflammatory regulation in older adults: evidence and utility. Rejuvenation Res. 2009 Dec;12(6):403-10. PMID: 20041734

Boyd C, Ricks M, Fried LP, Guralnik JM, Xue Q-L, Xia J, Bandeen-Roche K. Functional Decline And Recovery of Activities of Daily Living among Hospitalized, Disabled Older Women: The Women’s Health and Aging Study I. J Am Geriatr Soc. 2009 Aug 20. [Epub ahead of print]. PMID: 19694869

Cappola AR, Xue QL, Fried LP. Multiple hormonal deficiencies in anabolic hormones are found in frail older women: the Women's Health and Aging studies. J Gerontol A Biol Sci Med Sci. 2009 Feb;64(2):243-8. Epub 2009 Jan 31. PMID: 19182229

Carlson MC, Xue QL, Zhou J, & Fried LP. Executive Decline and Dysfunction Precedes Declines in Memory: The Women's Health and Aging Study II. J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):110-7. Epub 2009 Jan 31. PMID: 19182230.

Carlson MC, Erickson KI, Kramer AF, Voss MW, Bolea N, Mielke M, McGill S, Rebok GW, Seeman T, Fried LP. Evidence for neurocognitive plasticity in at-risk older adults: the experience corps program. J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1275-82. Epub 2009 Aug 19. PMID: 19692672

Chang SS, Weiss CO, Xue QL, Fried LP. Patterns of comorbid inflammatory diseases in frail older women: the Women's Health and Aging Studies I and II. J Gerontol A Biol Sci Med Sci. 2010 Apr;65(4):407-13. Epub 2009 Nov 23. PMID: 19933749.

Deal JA, Carlson MC, Xue QL, Fried LP, Chaves PH. Anemia and 9-year domain-specific cognitive decline in community-dwelling older women: The Women's Health and Aging Study II. J Am Geriatr Soc. 2009 Sep;57(9):1604-11. Epub 2009 Aug 13. PMID: 19682133.

Ferrucci L, Perry JR, Matteini A, Perola M, Tanaka T, Silander K, Rice N, Melzer D, Murray A, Cluett C, Fried LP, Albanes D, Corsi AM, Cherubini A, Guralnik J, Bandinelli S, Singleton A, Virtamo J, Walston J, Semba RD, Frayling TM. Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study. Am J Hum Genet. 2009 Feb;84(2):123-33. Epub 2009 Jan 29. PMID: 19185284.

Fallin MD, Matteini A. Genetic Epidemiology in Aging Research. class="journalname"J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):47-60. Epub 2009 Jan 23. PMID: 19168782.

Fried LP, Xue QL, Cappola AR, Ferrucci L, Chaves P, Varadhan R, Guralnik JM, Leng SX, Semba RD, Walston JD, Blaum CS, Bandeen-Roche K. Nonlinear multisystem physiological dysregulation associated with frailty in older women: implications for etiology and treatment. J Gerontol A Biol Sci Med Sci. 2009 Oct;64(10):1049-57. Epub 2009 Jun 30. PMID: 19567825.

Hsiao CJ, Bandeen-Roche K, Marsteller JA, Leff BA. The effect of disability on personal quality of primary care received by older adults. Disabil Rehabil. 2009;31(22):1835-42. PMID: 19479548.

Leng SX, Hung W, Cappola AR, Yu Q, Xue QL, Fried LP. White Blood Cell Counts, Insulinlike Growth Factor-1 Levels, and Frailty in Community-Dwelling Older Women. J Gerontol A Biol Sci Med Sci. 2009 Apr;64(4):499-502. Epub 2009 Feb 27. PMID: 19251912.

Leng SX, Xue QL, Tian J, Huang Y, Yeh SH, Fried LP. Associations of neutrophil and monocyte counts with frailty in community-dwelling disabled older women: results from the Women's Health and Aging Studies I. Exp Gerontol. 2009 Aug;44(8):511-6. Epub 2009 May 18. PMID: 19457449.

Mielke MM, Kozauer NA, Chan KC, George M, Toroney J, Zerrate M, Bandeen-Roche K, Wang MC, Vanzijl P, Pekar JJ, Mori S, Lyketsos CG, Albert M. Regionally-specific diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease. Neuroimage. 2009 May 15;46(1):47-55. Epub 2009 Feb 5. PMID: 19457371.

Qu T, Yang H, Walston JD, Fedarko NS, Leng SX. Upregulated monocytic expression of CXC chemokine ligand 10 (CXCL-10) and its relationship with serum interleukin-6 levels in the syndrome of frailty. Cytokine. 2009 Jun;46(3):319-24. Epub 2009 Apr 1. PMID: 19342252.

Semba RD, Ferrucci L, Sun K, Beck J, Dalal M, Varadhan R, Walston J, Guralnik JM, Fried LP. Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community-dwelling women. Aging Clin Exp Res. 2009 Apr;21(2):182-90. PMID: 19448391.

Szanton, S.L., Allen JK, Seplaki, CL, Bandeen-Roche K, Fried LP. Allostatic Load and Frailty in the Women’s Health and Aging Studies. Biol Res Nurs. 2009 Jan;10(3):248-56. Epub 2008 Sep 30. PMID: 18829589.

Tan EJ, Rebok GW, Yu Q, Frangakis CE, Carlson MC, Wang T, Ricks M, Tanner EK, McGill S, Fried LP. The Long-Term Relationship Between High-Intensity Volunteering and Physical Activity in Older African American Women. J Gerontol B Psychol Sci Soc Sci. 2009 Mar;64(2):304-11. Epub 2009 Jan 29. PMID: 19181687.

Thorpe RJ Jr, Weiss C, Xue QL, Fried LP. Transitions among disability levels or death in African American and white older women. J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):670-4. Epub 2009 Feb 19. PMID: 19228790.

Varadhan R, Chaves PH, Lipsitz LA, Stein PK, Tian J, Windham BG, Berger RD, Fried LP. Frailty and Impaired Cardiac Autonomic Control: New Insights From Principal Components Aggregation of Traditional Heart Rate Variability Indices. J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):682-7. Epub 2009 Feb 17. PMID: 19223607.

Varadhan R, Gilbert P. BB: An R Package for Solving a Large System of Nonlinear Equations and for Optimizing a High-Dimensional Nonlinear Objective Function. J Stat Soft. 2009 Oct;32(4):1-26.

Walston JD, Matteini AM, Nievergelt C, Lange LA, Fallin DM, Barzilai N, Ziv E, Pawlikowska L, Kwok P, Cummings SR, Kooperberg C, Lacroix A, Tracy RP, Atzmon G, Lange EM, Reiner AP. Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults. Exp Gerontol. 2009 May;44(5):350-5. Epub 2009 Feb 26. PMID: 19249341.

Xue, Q-L, Bandeen-Roche K. Latent variable regression analysis with missing covariates. Koln, Germany: Lambert Academic Publishing AG& Co. KG; 2009.

2008
Carlson MC, Helms MJ, Steffens DC, Burke JR, Potter GG,Plassman BL. Mid-life Activity Predicts Risk of Alzheimer’s Disease in Older Male Twin Pairs. Alzheimers Dement. 2008 Sep;4(5):324-31.PMID: 18790459.

Dayhoff-Brannigan M, Ferrucci L, Sun K, Fried LP, Walston J, Varadhan R, Guralnik JM, Semba RD. Oxidative protein damage is associated with elevated serum interleukin-6 levels among older moderately to severely disabled women living in the community. J Gerontol A Biol Sci Med Sci. 2008 Feb;63(2):179-83. PMID: 18314454

De Fanis U, Wang G, Fedarko N, Walston J, Casolaro V, and Leng SX. T-lymphocytes expressing CC chemokine receptor-5 are increased in frail older adults. J Am Geriatr Soc. 2008 May;56(5):904-8. Epub 2008 Apr 1. PMID: 18384587.

Espinoza SE, Guo H, Fedarko N, DeZern A, Fried LP, Xue QL, Leng S, Beamer B, Walston JD. Glutathione peroxidase enzyme activity in aging. J Gerontol A Biol Sci Med Sci. 2008 May;63(5):505-9. PMID: 18511755.

Evans WJ, Bhasin S, Cress C, Espeland MA, Ferrucci L, Fried LP, Gill G, Pahor M, Studenski S (Working Group on Functional Outcome Measures for Clinical Trials). Functional outcomes for clinical trials in frail older persons: time to be moving. J Gerontol A Biol Sci Med Sci. 2008 Feb;63(2):160-4. PMID: 18314451.

Matteini AM, Walston JD, Fallin MD, Bandeen-Roche K, Kao WHL, Semba RD, Allen RH, Guralnik J, Fried LP, Stabler SP. Markers of B-vitamin deficiency and frailty in older women. J Nutr Health Aging. 2008 May;12(5):303-8. PMID: 18443711.

Mielke MM, Xue QL, Zhou J, Chaves PH, Fried LP, Carlson MC. Baseline Serum Cholesterol Is Selectively Associated With Motor Speed and Not Rates of Cognitive Decline: The Women's Health and Aging Study II. J Gerontol A Biol Sci Med Sci. 2008 Jun;63(6):619-24.

Mielke MM, Bandaru VV, Haughey NJ, Rabins PV, Lyketsos CG, Carlson MC. Serum sphingomyelins and ceramides are early predictors of memory impairment. Neurobiol Aging. 2010 Jan;31(1):17-24. Epub 2008 May 5.PMID: 18455839.

Swihart BJ, Caffo B, Bandeen-Roche K, Punjabi NM. Characterizing sleep structure using the hypnogram. J Clin Sleep Med. 2008 Aug 15;4(4):349-55. PMID: 18763427.

Varadhan R, Seplaki CL, Xue QL, Bandeen-Roche K, Fried LP. Stimulus-response paradigm for characterizing the loss of resilience in homeostatic regulation associated with frailty. Mech Ageing Dev. 2008 Nov;129(11):666-70. Epub 2008 Sep 30.PMID: 18938195.

Varadhan R, Walston J, Cappola AR, Carlson MC, Wand GS, Fried LP. Higher Levels and Blunted Diurnal Variation of Cortisol in Frail Older Women. J Gerontol A Biol Sci Med Sci 2008 63: 190-195.

Varadhan R., Roland C. Simple and globally-convergent methods for accelerating the convergence of any EM algorithm. Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics, Finnish Statistical Society, Norwegian Statistical Association and Swedish Statistical Association, vol. 35(2), pages 335-353.

Walston J, Fedarko N, Yang H, Leng S, Beamer B, Espinoza S, Lipton A, Zheng H, Becker K. The physical and biological characterization of a frail mouse model. J Gerontol A Biol Sci Med Sci. 2008 Apr;63(4):391-8. PMID: 18426963.

Xue Q-L, Fried LP, Glass TA, Laffan AM, Chaves PHM. Life-space constriction, development of frailty, and the competing risk of mortality: the Women's Health And Aging Study I. Am J Epidemiol. 2008 Jan 15;167(2):240-8. Epub 2007 Sep 28. PMID: 17906296.

Xue Q-L, Bandeen-Roche K, Zhou J, Varadhan R, Fried LP. Initial manifestations of frailty criteria and the development of frailty phenotype in the Women’s Health and Aging Study II. J Gerontol A Biol Sci Med Sci. 2008 Sep;63(9):984-90.PMID: 18840805.

2007
Barzilay JI, Blaum C, Moore T, Xue Q-L, Hirsch CH, Walston JD, Fried LP. Insulin Resistance and Inflammation as Precursors of Frailty: The Cardiovascular Health Study. Arch Intern Med 2007; 167(7):635-41. PMID: 17420420.

Beck J, Ferrucci L, Sun K, Walston J, Fried LP, Varadhan R, Guralnik JM, Semba RD. Low serum selenium concentrations are associated with poor grip strength among older women living in the community. Biofactors. 2007;29(1):37-44. PMID: 17611292.

Boyd CM, Weiss CO, Halter J, Han KC, Ershler WB, Fried LP: Framework for Evaluating Disease Severity Measures in Older Adults with Comorbidity. J Gerontol A Biol Sci Med Sci. 2007, Vol. 62A, No. 3, 286–295. PMID: 17389726.

Chang DC, Joyce DL, Shoher A, Yuh DD. A Simple Index to Predict Likelihood of Skilled Nursing Facility Admission after CABG among Older Patients. Ann Thorac Surg. 2007 Sep;84(3):829-34; discussion 834-5. PMID: 17720384

Desquilbet L, Jacobson LP, Fried LP, Phair JP, Jamieson BD, Holloway M, Margolick JB; Multicenter AIDS Cohort Study. HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty. J Gerontol A Biol Sci Med Sci. 2007 Nov;62(11):1279-86. PMID: 18000149.

Folsom AR, Boland LL, Cushman M, Heckbert SR, Rosamond WD, Walston JD. Frailty and risk of venous thromboembolism in older adults. J Gerontol A Biol Sci Med Sci. 2007 Jan;62(1):79-82. PMID: 15066083.

Howard C, Ferrucci L, Sun K, Fried LP, Walston J, Varadhan R, Guralnik JM, Semba RD. Oxidative protein damage is associated with poor grip strength among older women living in the community. J Appl Physiol. 2007 Jul;103(1):17-20. Epub 2007 Mar 22. PMID: 17379753.

Leng SX, Xue Q-L, Tian J, Walston J, Fried LP. Inflammation and frailty in older women. J Am Geriatr Soc. 2007 Jun;55(6):864-71. PMID: 17537086.

Rebok GW, Carlson MC, & Langbaum JB. Training and maintaining memory abilities in healthy older adults: traditional and novel approaches. J Gerontol B Psychol Sci Soc Sci. 2007 Jun;62 Spec No 1:53-61. Review. PMID: 17565165.

Roland C., Varadhan R., and Frangakis C.E. Squared polynomial extrapolation methods with cycling: an application to the positron emission tomography problem, Numerical Algorithms, Volume 44, Number 2, February 2007, pp. 159-172.

Semba RD, Ferrucci L, Sun K, Walston J, Varadhan R, Guralnik JM, Fried LP. Oxidative stress and severe walking disability among older women. Am J Med. 2007 Dec;120(12):1084-9. PMID: 18060930.

Semba RD, Ricks MO, Ferrucci L, Xue QL, Guralnik JM, Fried LP. Low serum selenium is associated with anemia among older adults in the United States. Eur J Clin Nutr. 2007 Sep 5; [Epub ahead of print]. PMID: 17805227.

Walston JD, Fallin MD, Cushman M, Lange L, Psaty B, Jenny N, Browner W, Tracy R, Durda P, Reiner A. IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study. Hum Genet. 2007 Dec;122(5):485-94. Epub 2007 Sep 13. PMID: 17851695.

Weiss CO, Boyd CM, Yu Q, Wolff JL, Leff B. Patterns of prevalent major chronic disease among older adults in the United States. JAMA. 2007 Sep 12;298(10):1160-2. PMID: 17848649.

2006
Arking DE, Fallin DM, Li T, Beamer BA, Xue QL, Fried LP, Chakravarti A, Walston JD. Variation in the Ciliary Neurotrophic Factor Gene and Muscle Strength in Older Caucasian Women. Journal of the American Geriatrics Society, 2006; May;54(5):823-6. PMID: 16696750.

Bandeen-Roche K, Xue Q-L, Ferrucci L, Walston J, Guralnik JM, Chaves PHM, Zeger SL, Fried LP. Phenotype of Frailty: Characterization in the Women’s Health and Aging Studies. J Gerontol Med Sci, 2006 Mar;61(3):262-6. PMID: 16567375.

Bartali B, Frongillo EA, Bandinelli S, Lauretani F, Semba RD, Fried LP, Ferrucci L. Low nutrient intake is an essential component of frailty in older persons. J Gerontol: Med Sci. 2006 Jun;61(6):589-93. PMID: 16799141.

Chaves PHM, Carlson MC, Guralnik JM, Ferrucci L, Semba R, Fried LP. Association of Mild Anemia with Executive Cognitive Function Impairment in Community-Dwelling Older Women: The Women’s Health and Aging Study II. J Am Geriatr Soc. 2006 Sep;54(9):1429-35. PMID: 16970654.

Chi PB, Duggal P, Kao WH, Mathias RA, Grant AV, Stockton ML, Garcia JG, Ingersoll RG, Scott AF, Beaty TH, Barnes KC, Fallin MD. Comparison of SNP tagging methods using empirical data: association study of 713 SNPs on chromosome 12q14.3-12q24.21 for asthma and total serum IgE in an African Caribbean population. Genet Epidemiol. 2006 Nov: 30(7):609-19. PMID: 16830339.

Kim DH, Lipsitz LA, Ferrucci L, Guralnik JM, Carlson M, Fleisher LA, Fried LP, Chaves PHM. Association of Reduced Heart Rate Variability with Cognitive Impairment in Older Disabled Women in the Community: A Pilot Study in the Women’s Health and Aging Study I. J Am Geriatr Soc. 2006 Nov;54(11):1751-7. PMID: 17087704.

Ling SM, Xue QL, Simonsick EM, Tian J, Bandeen-Roche K, Fried LP, Bathon JM. Transitions to mobility difficulty associated with lower extremity osteoarthritis in high functioning older women: longitudinal data from the Women's Health and Aging Study II. Arthritis Rheum. 2006 Apr 15;55(2): 256-63. PMID: 16583416.

Michelon E, Blaum C, Semba RD, Xue QL, Ricks MO, Fried LP. Vitamin and carotenoid status in older women: associations with the frailty syndrome. J Gerontol A Biol Sci Med Sci. 2006 Jun;61(6):600-7. PMID: 16799143.

Studenski S, Carlson MC, Fillit H, Greenough WT, Kramer A, Rebok GW.. From bedside to bench: does mental and physical activity promote cognitive vitality in late life? Sci Aging Knowledge Environ 2006. 28; (10): 21. PMID: 16807485.

Tan EJ, Xue QL, Li T, Carlson MC, Fried LP. Volunteering: a physical activity intervention for older adults--The Experience Corps program in Baltimore. J Urban Health. 2006 Sep;83(5):954-69. PMID: 16763775.

Walston J, Hadley EC, Ferrucci L, Guralnik J, Newman, AB, Studenski S, Ershler W, Harris T, Fried LP. Research agenda for Frailty in Older Adults: Towards a Better Understanding of Physiology and Etiology. J Am Geriatr Soc. 2006 Jun;54(6):991-1001. PMID: 16776798.

Walston J, Xue Q-L, Semba RD, Ferrucci L, Cappola AR, Ricks M, Guralnik JM, Fried LP. Serum Antioxidants, Inflammation, and Mortality in Older Women. American Journal of Epidemiology 2006:Jan1;163(1):18-26. PMID: 16306311.

2005
Benke KS, Chase GA, Fallin D. Use of susceptibility scoring in conjunction with the genotypic transmission disequilibrium test. BMC Genet. 2005 Dec 30;6 Suppl 1:S137. PMID: 16451596

Blaum CS, Xue Q-L, Michelon E, Semba RD, Fried LP. The association of obesity and the frailty syndrome in older women. The Journal of the American Geriatrics Society 2005 June; 53(6):927-34. PMID: 15935013.

Boyd CM, Darer J, Boult C, Fried LP, Boult L, Wu A. Clinical Practice Guidelines and Quality of Care for Older Patients With Multiple Comorbid Diseases: Implications for Pay for Performance. JAMA, August 10, 2005:294:5:716-724. PMID: 16091574.

Boyd CM, Xue Q-L, Simpson CF, Guralnik JM, Fried LP. Frailty, hospitalization and progression of disability in a cohort of disabled older women: The Women’s Health and Aging Study I. The American Journal of Medicine, 2005 Nov;118(11):1225-31. PMID: 16271906.

Chaves PH, Semba RD, Leng SX, Woodman RC, Ferrucci L, Guralnik JM, Fried LP. Impact of Anemia and Cardiovascular Disease on Frailty Status of Community-Dwelling Older Women: The Women’s Health and Aging Studies I and II. J Gerontol Med Sci, 2005 June;60A:6:729-735. PMID: 15983175.

Fried LP, Hadley EC, Walston JD, Newman A, Guralnik JM, Studenski S, Harris TB, Ershler WB, Ferrucci L. From bedside to bench: research agenda for frailty. Sci Aging Knowledge Environ. 2005 Aug 3;2005(31):pe24. PMID: 16079413.

Leng SX, Xue Q-L, Huang Y, Ferrucci L, Beamer BA, Fried LP, Walston J. Baseline Total and Specific Differential White Blood Cell Counts and 5-year All-Cause Mortality in Community-Dwelling Older Women. Experimental Gerontology, 2005 Dec, (40):982-987. PMID: 16183235.

Leng SX, Xue Q-L, Huang Y, Semba R, Chaves P, Bandeen-Roche K, Fried LP, Walston J. Total and differential WBC counts and their associations with circulating IL-6 levels in community-dwelling older women. J Gerontol Med Sci, 2005;60A:195-199.

Nicodemus KK, Liu W, Chase GA, Tsai YY, Fallin MD. Comparison of type I Error for Multiple Test Corrections in Large SNP Studies Using Principal Components Versus Haplotype Blocking Algorithms. BMC Genetics 2005 Dec: 6 Suppl 1:S78. PMID: 16451692

Walston J, Arking DE, Fallin D, Li T, Beamer B, Xue Q, Ferrucci L, Fried LP, Chakravarti A. IL-6 Gene Variation is not Associated with Increased Serum Levels of IL-6, muscle weakness, or frailty in older women. Experimental Gerontology, 2005; 40:344-352. PMID: 15820616.

Wang C-P, Brown CH, Bandeen-Roche K. Residual Diagnostics for Growth Mixture Models: Examining the Impact of a Preventive Intervention on Multiple Trajectories of Aggressive Behavior. Journal of the American Statistical Association, 2005 Sep;100(3):1054-1076.

Yuh DD, Baumgartner WA. Cardiac Surgery in the Elderly. In: Gerstenblith G, ed. Cardiovascular Disease in the Elderly. Totowa, NJ, Humana Press, Inc. 2005 June: pp. 179-201.