Research Center Development Core
Overview
Key Accomplishments
Available Resources
Key Personnel

Past and Current Projects:
Supported Junior Faculty 

06/01/2003-05/31/2004 (Year 1)

• Boyd, Cynthia: “Characterization of functional decline and recovery after hospitalization”
• Carlson, Michelle: “Characterize cognitive reserve by examining with-cognitive-tests performance decays over time”
• Chaves, Paulo: “Heart Rate (HR) Variability and Complexity and Frailty Status in Older Women”
• Leng, Sean: “Contributions of serum IL-6 level and total/differential WBC to frailty and mortality”
• Yuh, David: “Impact of Frailty on Outcomes in Older Patients Undergoing Cardiac Surgery”

06/01/2004-05/31/2005 (Year 2)

• Boyd, Cynthia: “Characterization of functional decline and recovery after hospitalization”
• Carlson, Michelle: “Characterize cognitive reserve by examining with-cognitive-tests performance decays over time”
• Chaves, Paulo: “Heart Rate (HR) Variability and Complexity and Frailty Status in Older Women”
• Leng, Sean: “Contributions of serum IL-6 level and total/differential WBC to frailty and mortality”
• Yuh, David: “Impact of Frailty on Outcomes in Older Patients Undergoing Cardiac Surgery”

06/01/2005-05/31/2006 (Year 3)

• Boyd, Cynthia: “Characterization of functional decline and recovery after hospitalization”
• Carlson, Michelle: “Characterize cognitive reserve by examining with-cognitive-tests performance decays over time”
• Leng, Sean: “Contributions of serum IL-6 level and total/differential WBC to frailty and mortality”
• Yuh, David: “Impact of Frailty on Outcomes in Older Patients Undergoing Cardiac Surgery”

06/01/2006-05/31/2007 (Year 4)

• Crentsil, Victor: “L-carnitine deficiency and the development of frailty and disability in   older adults”
• Makary, Martin: “Frailty Syndrome in Surgical Patients”
• Seplaki, Chris: “Expanding the scope of frailty research: modeling multiple physiological systems, delineation among alternative frameworks, and the social context of frailty”
• Weiss, Carlos: “The Relationship between Frailty and Basal Metabolic Rate”

06/01/2007-05/31/2008 (Year 5)

• Makary, Martin: “Frailty Syndrome in Surgical Patients”
• Polotsky, Vsevolod: “Effect of Chronic Intermittent Hypoxia on Frailty”
• Seplaki, Chris: “Expanding the scope of frailty research: modeling multiple physiological systems, delineation among alternative frameworks, and the social context of frailty”
• Varadhan, Ravi: “Identifying frailty using non-invasively measured dynamic physiological signals”
• Weiss, Carlos: “The Relationship between Frailty and Basal Metabolic Rate”

07/01/2008-06/30/2009 (Year 6)

• Roy, Cindy : “Mechanisms of anemia associated with chronic inflammation and aging in mice”
• Tan, Erwin: “Effect of the Baltimore Experience Corps Study on Walking Activity and the Characteristics of Walking”
• Wang, George: “Potential targets along the pathophysiologic pathway of frailty amenable to preventive and therapeutic interventions"

07/01/2009-06/30/2010 (Year 7)

• Roy, Cindy : “Mechanisms of anemia associated with chronic inflammation and aging in mice”
• Tan, Erwin: “Effect of the Baltimore Experience Corps Study on Walking Activity and the Characteristics of Walking”
• Wang, George: “Potential targets along the pathophysiologic pathway of frailty amenable to preventive and therapeutic interventions"

07/01/2010-06/30/2011 (Year 8)

• Abadir, Peter : “Age Related Change in Angiotensin Receptors and Its Contribution to Chronic Inflammation” (received K23 award)
• Dobrosielski, Devon: “Effects of a Lifestyle Intervention in Older Adults with Sleep Apnea”
• Lin, Frank: “Hearing Loss and Frailty" (received K23 award)
• Pustavoitau, Aliaksei: “A Prospective Cohort Study Evaluating the Use of p16INK4a Transcriptional Factor Level as a Marker of Molecular Age and Predictor of Perioperative Outcomes”
• Roy, Cindy : “Mechanisms of anemia associated with chronic inflammation and aging in mice”
• Wang, George: “Long-term maintenance of viral T-cell immunity and T-cell repertoire diversity in the aging immune system"  (received K23 award)