The Johns Hopkins Older Americans’ Independence Center (OAIC) is soliciting proposals for support of scientific projects and junior investigators in the area of research on frailty in aging. The OAIC is a Johns Hopkins-wide Center funded by the National Institute on Aging of the NIH, through the Center on Aging and Health, to support the development of research on the etiology of frailty, as a basis for developing treatments, or approaches to prevention of frailty, in older adults. Scientists with an interest in developing pilot projects in this area or with needs for support of biostatistical or genetic analyses of data related to frailty, as well as junior faculty seeking protected time to develop investigative careers in this field, are encouraged to apply for internal funding through the OAIC mechanisms. Further information and due dates for proposals are stated in each of the five RFPs: Biostatistics Core Development Project, Biostatistics Core Supported Projects, Genetics Core Projects, Genetics Core Development Projects, and Junior Faculty Career Development. For instructions on submitting proposals, please refer to the Submission Guidelines. Please note that there are currently no request for proposals for the Pilot/Exploratory Studies Core. For additional information, contact Brian Buta, OAIC Administrator at bbuta1@jhmi.edu, Dr. Linda Fried, Principal Investigator at lfried@jhmi.edu, or the Directors of each respective core program, who are indicated on each specific request for proposal. Frailty in older adults is a biologically and physiologically-based syndrome that appears to result in an aggregate clinical presentation of loss of muscle mass, weakness, decreased energy and reserves—or sense of “exhaustion,” slowed motor performance, low physical activity and, in end stages, weight loss. Mounting scientific evidence indicates that this is a syndrome and that it is associated with dysregulation of multiple physiologic systems, in association of with aging and perhaps exacerbated by (endstage) disease. References on research on frailty from the Johns Hopkins Older Americans’ Independence Center follow: |
