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| Esther Oh, MD Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine (Primary appointment) Division of Neuropathology, Johns Hopkins University School of Medicine (Secondary appointment) Research Interest Dr. Oh's research interest is in developing biological marker for pre-clinical stage of Alzheimer's disease (AD). Her current research involves using transgenic models of AD to develop peripheral injection of monoclonal antibody against amyloid-beta as a tool to detect a level of amyloid-beta that would be correlative to? amyloid-beta level in the brain. Her clinical practice is in the Memory clinic at the Johns Hopkins University.
Publications Peer-Reviewed Scientific Articles: 1. Tabuchi A, Sano K, Oh E, Tsuchiya T, Tsuda M. Modulation of AP-I activity by nitric oxide (NO) in vitro: NO-mediated modulation of AP-I. FEBS Letters, 1994; 351:123-127. 2. Ohtani K, Sakurai H, Oh E, Iwata E, Tsuchiya T, Tsuda M. Involvement of protein kinase C in calcium signaling pathway to activation of AP-I DNA-binding activity evoked via NMDA and voltage-gated calcium channels. Journal of Neurochemistry, 1995;65(2):605-614. 3. Tabuchi A, Oh E, Taoka A, Sakurai H, Tsuchiya T, Tsuda M. Rapid attenuation of AP-I transcriptional factors associated with nitric oxide (NO) mediated neuronal cell death. The Journal of Biological Chemistry, 1996; 271:31061-31067. 4. Oh ES, Savonenko AV, King JF, Tucker SM, Rudow GL, Xu G, Borchelt DR, Troncoso JC. Amyloid Precursor Protein Increases Cortical Neuron Size in Transgenic Mice Neurobiology of Aging, Epub (2/08) in press 5. Oh ES, Troncoso JC, Fangmark Tucker SM. Maximizing the potential of plasma amyloid-beta as a diagnostic biomarker for Alzheimer's disease, Neuromolecular Medicine, 2008;10 (3):195-207 PMC2558671. Abstracts: 1. E. Oh, S. Tucker, A. Smith, D. Borchelt, J. Troncoso. Biotinylated anti-A antibody as a tool to diagnose pre-clinical Alzheimer's disease (AD). (Submitted 36th Annual Meeting of the Society for Neuroscience, Oct, 2006). 2. E. Oh, S.Tucker, M. Riudavets, D. Borchelt, J.Troncoso. The Effect of Anti-amyloid beta Antibody 7B6 on Neuronal Cell Volume. J Am Geriatr. Soc. 2006:54.S156 (Selected for Presidential Poster Session) 3. Esther S. Oh, Stina M Tucker, Gay L Rudow, Joanna L Jankowsky, David R Borchelt, Juan C Troncoso. Passive immunization with monoclonal antibody Ab 1-11 in transgenic mouse models of Alzheimer's disease. American Association of Neuropathologists 2005 Annual Meeting. June 9-12, 2005. (Podium presentation) 4. Oh, Esther S., Tucker, Stina, Jankowsky, Joanna, Borchelt, David, and Troncoso, Juan. Peripheral administration of monoclonal antibody as a diagnostic tool to detect soluble amyloid beta. J Am Geriatr Soc., 2005; 53, S19. (Poster presentation) 5. Khan A, Oh E, Weisman D, Lesky L. End-Of-Life Curriculum Development at a University Hospital. The Journal of Palliative Medicine, 2001;4:4,533. 6. Hiroaki Sakurai, Esther Oh, Kuniaki Sano, Akiko Tabuchi, Tomofusa Tsuchiya and Masaaki Tsuda. Induction of TRE Binding Activities Mediated by Glutamate Receptors and Its Regulation by Nitric Oxide (NO). Japanese Biochemical Society Meeting. December 9-12, 1992. 7. Hiroaki Sakurai, Esther Oh, Kuniaki Sano, Tomofusa Tsuchiya and Masaaki Tsuda. Induction of Novel DNA-Binding Activity in the Cerebellar Granule Cells Stimulated via Glutamate Receptors. 1st UBMB Conference, Biochemistry of Diseases, June 1, 1992. Honors and Awards John A. Hartford Foundation Fellowship in Geriatric Medicine, 1990 Keywords |
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