Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine (Primary appointment) Division of Neuropathology, Johns Hopkins University School of Medicine (Secondary appointment) Dr. Oh’s research interest is in developing biological marker for pre-clinical stage of Alzheimer’s disease (AD). Her current research involves using transgenic models of AD to develop peripheral injection of monoclonal antibody against amyloid-beta as a tool to detect a level of amyloid-beta that would be correlative to amyloid-beta level in the brain. Her clinical practice is in the Memory clinic at the Johns Hopkins University. Academic Degrees
Email: eoh9@jhmi.edu
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Pager: (410) 283-8578 Peer-Reviewed Scientific Articles: 1. Akiko Tabuchi, Esther Oh, Akiko Taoka, Hiroaki Sakurai, Tomofusa Tsuchiya, and Masaaki Tsuda. Rapid Attenuation of AP-I Transcriptional Factors Associated with Nitric Oxide (NO) – Mediated Neuronal Cell Death. The Journal of Biological Chemistry, 1996;271:31061-31067. 2. Ohtani K, Sakurai H, Oh E, Iwata E, Tsuchiya T, Tsuda M. Involvement of Protein Kinase C in Calcium Signaling Pathway to Activation of AP-I DNA-binding Activity Evoked via NMDA and Voltage-gated Calcium Channels. Journal of Neurochemistry, 1995;65(2):605-614. 3. Akiko Tabuchi, Kuniaki Sano, Esther Oh, Tomofusa Tsuchiya, Masaaki Tsuda. Modulation of AP-I Activity by Nitric Oxide (NO) in vitro: NO-Mediated Modulation of AP-I. FEBS Letters, 1994;351:123-127. 1. E. Oh, S. Tucker, A. Smith, D. Borchelt, J. Troncoso. Biotinylated anti-Aβ antibody as a tool to diagnose pre-clinical Alzheimer’s disease (AD). (Submitted 36th Annual Meeting of the Society for Neuroscience, Oct, 2006) 2. E. Oh, S.Tucker, M. Riudavets, D. Borchelt, J.Troncoso. The Effect of Anti-amyloid beta Antibody 7B6 on Neuronal Cell Volume. J Am Geriatr. Soc. 2006:54.S156 (Selected for Presidential Poster Session) 3. Esther S. Oh, Stina M Tucker, Gay L Rudow, Joanna L Jankowsky, David R Borchelt, Juan C Troncoso. Passive immunization with monoclonal antibody Ab 1-11 in transgenic mouse models of Alzheimer’s disease. American Association of Neuropathologists 2005 Annual Meeting. June 9-12, 2005. (Podium presentation)
4. Oh, Esther S., Tucker, Stina, Jankowsky, Joanna, Borchelt, David, and Troncoso, Juan. Peripheral administration of monoclonal antibody as a diagnostic tool to detect soluble amyloid beta. J Am Geriatr Soc., 2005; 53, S19. (Poster presentation)
5. Khan A, Oh E, Weisman D, Lesky L. End-Of-Life Curriculum Development at a University Hospital. The Journal of Palliative Medicine, 2001;4:4,533. 6. Hiroaki Sakurai, Esther Oh, Kuniaki Sano, Akiko Tabuchi, Tomofusa Tsuchiya and Masaaki Tsuda. Induction of TRE Binding Activities Mediated by Glutamate Receptors and Its Regulation by Nitric Oxide (NO). Japanese Biochemical Society Meeting. December 9-12, 1992. 7. Hiroaki Sakurai, Esther Oh, Kuniaki Sano, Tomofusa Tsuchiya and Masaaki Tsuda. Induction of Novel DNA-Binding Activity in the Cerebellar Granule Cells Stimulated via Glutamate Receptors. 1st UBMB Conference, Biochemistry of Diseases, June 1, 1992. John A. Hartford Foundation Fellowship in Geriatric Medicine, 1990
de Kiewiet Summer Research Scholarship, 1990
Okayama University International Exchange Scholarship, 1992
National Institute of Health (NIH) Summer Research Fellowship, 1995
National Institute on Aging (NIA) Research Training in Gerontology and Geriatric Medicine 2002-2004
Technical Assistance Workshop, National Institute on Aging (NIA) 2003
Summer Institute on Aging Research (NIA) 2005 Keywords
Alzheimer’s disease, dementia, biomarker, transgenic mouse model of Alzheimer’s disease |
